Cefoxitin

• Description:

  Cefoxitin is a cephalosporin-class antibiotic. Cefoxitin is highly stable against β-Lactamase (HY-P2998) . Cefoxitin has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria[1][2][3].

• UNSPSC:

  12352005

• Hazard Statement:

  H317, H334

• Target:

  Antibiotic; Bacterial; Beta-lactamase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/cefoxitin.html

• Concentration:

  10mM

• Purity:

  99.92

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@@](NC(CC3=CC=CS3)=O)(OC)C1=O)O

• Molecular Formula:

  C16H17N3O7S2

• Molecular Weight:

  427.45

• Precautions:

  H317, H334

• References & Citations:

  [1]E O Stapley, et al. Cefoxitin and cephamycins: microbiological studies. Rev Infect Dis. Jan-Feb 1979;1 (1) :73-89.|[2]R N Brogden, et al. Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1979 Jan;17 (1) :1-37.|[3]Venkata Raveendra Pothineni, et al. In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. Drug Des Devel Ther. 2018; 12: 2915–2921.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Citation 01:

  Antimicrob Agents Chemother. 2025 May 23:e0024925.|bioRxiv. 2025 Jun 19.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|Infect Drug Resist. 2025 Oct 4:18:5239-5247.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|J Clin Microbiol. 2025 Aug 20:e0084125.|Microbiol Spectr. 2025 May 19:e0307424.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Nat Commun. 2023 Mar 22;14 (1) :1594.|Nat Microbiol. 2023 Mar;8 (3) :410-423.|J Antimicrob Chemother. 2020 Jul 1;75 (7) :1850-1858.

• CAS Number:

  35607-66-0