Pirlimycin (hydrochloride)

• UNSPSC Description:

  Pirlimycin hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].

• Target Antigen:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/pirlimycin-hydrochloride.html

• Purity:

  100

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H]1C[C@@H](CCN1)CC)N[C@]([C@@]2([H])O[C@@H]([C@H](O)[C@@H](O)[C@H]2O)SC)([H])[C@@H](Cl)C.Cl

• Molecular Weight:

  447.42

• References & Citations:

  [1]Birkenmeyer RD, et, al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem. 1984 Feb;27(2):216-23.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  78822-40-9