DC-Chol (hydrochloride)

DC-Chol (hydrochloride)

• CAS Number: 166023-21-8
• UNSPSC Description: DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner[1][2].
• Target Antigen: Amyloid-β; Liposome
• Type: Oligonucleotides
• Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/dc-chol-hydrochloride.html
• Smiles: CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](OC(NCCN(C)C)=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C.[H]Cl
• Molecular Weight: 537.26
• References & Citations: [1]Esmail A Elbassal, et al. Effects of Charged Cholesterol Derivatives on Aβ40 Amyloid Formation. J Phys Chem B. 2016 Jan 14;120(1):59-68.|[2]Richard Lantz, et al. Effects of disulfide bond and cholesterol derivatives on human calcitonin amyloid formation. Biopolymers. 2020 May;111(5):e23343.
• Shipping Conditions: Room Temperature