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MAP2 (Phospho-Thr1616) rabbit pAb

CAT: 0855-ES15040-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
Description
This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],
UniProt
P11137
Swiss Prot
P11137
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human MAP2 (Phospho-Thr1616)
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; WB
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, WB 1:500-2000
Molecular Weight
280kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
280kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cell projection, dendrite .
Other Product Names
Microtubule-associated protein 2 (MAP-2)
Gene ID (Human)
4133

UniProtKB · P11137

Microtubule-associated protein 2

MTAP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11137
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MAP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
MAP-2
EC number
—
Processing
—
Secondary accessions
Q17S04, Q8IUX2, Q99975, Q99976
Protein keywords

Coding sequence diversity

Alternative splicing

Molecular function

Calmodulin-binding

Cellular component

Cell projectionCytoplasmCytoskeletonMicrotubule

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

Repeat

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