MAP2 (phospho-Ser136) rabbit pAb

• Background:

  This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]

• Description:

  This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010],

• Synonyms:

  Microtubule-associated protein 2 (MAP-2)

• Gene ID:

  4133

• UniProt:

  P11137

• Cellular Locus:

  Cytoplasm, cytoskeleton. Cell projection, dendrite.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat

• Reactivity:

  Human; Rat

• Immunogen:

  Synthesized phosho peptide around human MAP2 (Ser136)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB

• Validated Applications:

  WB

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000-2000

• Molecular Weight:

  200kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  200 kD

• Subcellular Location:

  Cytoplasm, cytoskeleton . Cell projection, dendrite .

• Other Product Names:

  Microtubule-associated protein 2 (MAP-2)

• Gene ID (Human):

  4133

• SwissProt (Human):

  P11137