Tubulin polymerization-IN-65

• UNSPSC Description:

  Tubulin polymerization-IN-65 is a tubulin polymerisation inhibitor with a broad spectrum cytotoxic. Tubulin polymerization-IN-65 induces G2 + M cell cycle arrest[1].

• Target Antigen:

  Microtubule/Tubulin

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Cytoskeleton

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tubulin-polymerization-in-65.html

• Smiles:

  O=C1NC(/C=C/C2=CC=CC=C2OC)=NC3=CC=CC=C31

• Molecular Weight:

  278.31

• References & Citations:

  [1]Nicholas S O'Brien, et al. 2,3-Dihydroquinazolin-4(1 H)-ones and quinazolin-4(3 H)-ones as broad-spectrum cytotoxic agents and their impact on tubulin polymerisation. RSC Med Chem. 2024 Mar 6;15(5):1686-1708.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported