Products for Research Use Only

LY52

CAT: 0804-HY-119110Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-119110Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY52 is an MMP-2 and MMP-9 inhibitor. LY52 can significantly block the proteolytic activity of gelatinases, reducing the expression of MMP-2 and MMP-9 in SKOV3 cells, thereby inhibiting cell invasion. LY52 can also suppress the pulmonary metastasis of Lewis lung carcinoma cells in mice. LY52 may be used in cancer research[1].
CAS Number
769970-91-4
UNSPSC
12352005
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ly52.html
Smiles
O=C(N[C@@H]1CN([C@@H](C1)C(NO)=O)C(/C=C/C2=CC=C(C(OC)=C2)OC)=O)C3=CC=CN=C3
Molecular Formula
C22H24N4O6
Molecular Weight
440.45
References & Citations
[1]Qu X, et al. Caffeoyl pyrrolidine derivative LY52 inhibits tumor invasion and metastasis via suppression of matrix metalloproteinase activity. Anticancer Res. 2006 Sep-Oct;26 (5A) :3573-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-2; MMP-9

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