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LY5

CAT: 0804-HY-12442-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12442-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY5 is a STAT3 inhibitor with an IC50 value of 0.5 μM. LY5 induces apoptosis and inhibits STAT3 phosphorylation. LY5 shows antitumor activity in vivo, it can be used for the research of cancer[1].
CAS Number
1436382-03-4
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ly5.html
Purity
97.02
Solubility
DMSO : 6.25 mg/mL (ultrasonic)
Smiles
NS(=O)(C1=C2C(C(C(NC3=CC=CN=C3)=CC2=O)=O)=CC=C1)=O
Molecular Formula
C15H11N3O4S
Molecular Weight
329.33
References & Citations
[1]Yu W, et al. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design. J Med Chem. 2013 Jun 13;56 (11) :4402-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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