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Carubicin

CAT: 0804-HY-B2171-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B2171-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Carubicin (Carminomycin) is a microbially-derived compound. Carubicin is an effective inhibitor of VHL-defective (VHL−/−) CCRCC cell proliferation. Carubicin also induces apoptosis by a mechanism independent of p53 or hypoxia-inducible factor HIF2. Carubicin has the potential for the research of cancer diseases[1][2].
CAS Number
50935-04-1
Product Name Alternative
Carminomycin; Carminomicin I
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/carubicin.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C(C(C3=C(O)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)=C1C[C@](O)(C4)C(C)=O
Molecular Formula
C26H27NO10
Molecular Weight
513.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1][1]Woldemichael GM, et al. Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Res. 2011 Jan 1;71 (1) :134-42.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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