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MKI-1

CAT: 0804-HY-137552-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137552-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MKI-1, an inhibitor of MASTL (microtubule-associated serine/threonine kinase-like) with an IC50 of 9.9 μM, exerts antitumor and radiosensitizer activities through PP2A activation in breast cancer[1].
CAS Number
1190277-80-5
Product Name Alternative
MASTL Kinase Inhibitor-1
UNSPSC
12352005
Target
MASTL
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mki-1.html
Purity
98.07
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=NC2=CC=CC=C2N1)C3=CC=CC(N4C=CC=C4)=C3
Molecular Formula
C18H14N4O
Molecular Weight
302.33
References & Citations
[1]Ah-Young Kim, et al. MKI-1, a Novel Small-Molecule Inhibitor of MASTL, Exerts Antitumor and Radiosensitizer Activities Through PP2A Activation in Breast cancer. Front Oncol. 2020 Sep 29;10:571601.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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