DMT-2'O-MOE-rG(ib) Phosphoramidite

DMT-2'O-MOE-rG(ib) Phosphoramidite

• CAS Number: 251647-55-9
• UNSPSC Description: DMT-2'O-MOE-rG(ib) Phosphoramidite (1g), belonging to the amide family of trivalent phosphate H3PO3, is a derivative of nucleotides and guanosine and can be used in the stereochemical synthesis of phosphorothioate oligonucleotides[1].
• Target Antigen: DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dmt-2-o-moe-rg-ib-phosphoramidite.html
• Purity: 95.01
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O
• Molecular Weight: 913.99
• References & Citations: [1]Vasulinga T, et al. Stereoselective Synthesis of Alkylphosphonates:  A Facile Rearrangement of Cyanoethyl-Protected Nucleoside Phosphoramidites. Org. Proc. Res. Dev. 2004, 8, 4, 603–608
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported