RXFP3/4 agonist 2

RXFP3/4 agonist 2

• CAS Number: 2752378-78-0
• UNSPSC Description: RXFP3/4 agonist 2 is a potent, nonpeptide dual RXFP3/4 agonist (EC50=3.1 and 2.7 nM). RXFP3/4 agonist 2 also potently promotes interactions between RXFP3 and β-arrestin-2 with EC50 values in the range of 10-22 nM[1].
• Target Antigen: RXFP Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/rxfp3-4-agonist-2.html
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: COC(C(C=C1)=CC=C1CCNC(N/N=C/C(C2=CC(C#N)=C3)=CNC2=C3C)=N)=O
• Molecular Weight: 402.45
• References & Citations: [1]Guan D, et al. Indole-Containing Amidinohydrazones as Nonpeptide, Dual RXFP3/4 Agonists: Synthesis, Structure-Activity Relationship, and Molecular Modeling Studies. J Med Chem. 2021;64(24):17866-17886.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported