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ZCHC8 Polyclonal Antibody

CAT: 0749-ABP60959-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60959-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZCCHC8 (Zinc Finger CCHC-Type Containing 8) is a Protein Coding gene. ZCCHC8 encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain.
Description
Rabbit Anti-ZCHC8 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8
Gene ID
55596
Accession Number
Q6NZY4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human ZCHC8 protein
Clonality
Polyclonal
Tag
ZCHC8
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
77kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ZCHC8 protein
Observed Molecular Weight
77
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Zinc finger CCHC domain-containing protein 8; TRAMP-like complex RNA-binding factor ZCCHC8
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6NZY4
Isotype
Rabbit IgG

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