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VNN2 Polyclonal Antibody

CAT: 0749-ABP60897-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60897-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
VNN2 product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. VNN2 lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for VNN2.
Description
Rabbit Anti-VNN2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Vascular non-inflammatory molecule 2; Vanin-2; Glycosylphosphatidyl inositol-anchored protein GPI-80; Protein FOAP-4
Gene ID
8875
Accession Number
O95498
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human VNN2 protein at amino acid sequence of 320-400
Clonality
Polyclonal
Tag
VNN2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
57kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of VNN2 protein
Observed Molecular Weight
57
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Vascular non-inflammatory molecule 2; Vanin-2; Glycosylphosphatidyl inositol-anchored protein GPI-80; Protein FOAP-4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O95498
Isotype
Rabbit IgG

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