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VATC1 Polyclonal Antibody

CAT: 0749-ABP60875-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60875-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ATP6V1C1 (ATPase H+ Transporting V1 Subunit C1) is a Protein Coding gene. Among its related pathways are Rheumatoid arthritis and mTOR signaling pathway (KEGG) . ATP6V1C1 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c" and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. ATP6V1C1 is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, ATP6V1C1 was designated ATP6D.
Description
Rabbit Anti-VATC1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
V-type proton ATPase subunit C 1; V-ATPase subunit C 1; Vacuolar proton pump subunit C 1
Gene ID
528
Accession Number
P21283
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human VATC1 protein
Clonality
Polyclonal
Tag
VATC1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of VATC1 protein
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
V-type proton ATPase subunit C 1; V-ATPase subunit C 1; Vacuolar proton pump subunit C 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P21283
Isotype
Rabbit IgG

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