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UBQL2 Polyclonal Antibody

CAT: 0749-ABP60844-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60844-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UBQLN2 (Ubiquilin 2) is a Protein Coding gene. Diseases associated with UBQLN2 include Amyotrophic Lateral Sclerosis 15, With Or Without Frontotemporal Dementia and Ubqln2-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia. Among its related pathways are Protein processing in endoplasmic reticulum and Clathrin-mediated endocytosis. UBQLN2 encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases; and thus, are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to bind the ATPase domain of the Hsp70-like Stch protein.
Description
Rabbit Anti-UBQL2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ubiquilin-2; Chap1; DSK2 homolog; Protein linking IAP with cytoskeleton 2; PLIC-2; hPLIC-2; Ubiquitin-like product Chap1/Dsk2
Gene ID
29978
Accession Number
Q9UHD9
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human UBQL2 protein
Clonality
Polyclonal
Tag
UBQL2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
68kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of UBQL2 protein
Observed Molecular Weight
68
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ubiquilin-2; Chap1; DSK2 homolog; Protein linking IAP with cytoskeleton 2; PLIC-2; hPLIC-2; Ubiquitin-like product Chap1/Dsk2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UHD9
Isotype
Rabbit IgG

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