TM2D1 Polyclonal Antibody

CAT: 0749-ABP60706-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60706-01Size:30 µL
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Background
The protein encoded by TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for TM2D1.
Description
Rabbit Anti-TM2D1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
TM2 domain-containing protein 1; Amyloid-beta-binding protein; hBBP
Gene ID
83941
Accession Number
Q9BX74
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human TM2D1 protein
Clonality
Polyclonal
Tag
TM2D1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TM2D1 protein
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
TM2 domain-containing protein 1; Amyloid-beta-binding protein; hBBP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9BX74
Isotype
Rabbit IgG

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