THOP1 Polyclonal Antibody

• Background:

  Thimet Oligopeptidase 1 encoded by THOP1 is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. Thimet Oligopeptidase 1 also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. THOP1 (Thimet Oligopeptidase 1) is a Protein Coding gene. Among its related pathways are African trypanosomiasis and ACE Inhibitor Pathway, Pharmacodynamics.

• Description:

  Rabbit Anti-THOP1 Polyclonal Antibody

• Product Name Alternative:

  Thimet oligopeptidase; Endopeptidase 24.15; MP78

• Gene ID:

  7064

• Accession Number:

  P52888

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human THOP1 protein

• Clonality:

  Polyclonal

• Tag:

  THOP1

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  75kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of THOP1 protein

• Observed Molecular Weight:

  75

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Thimet oligopeptidase; Endopeptidase 24.15; MP78

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P52888

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG