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TGIF2 Polyclonal Antibody

CAT: 0749-ABP60668-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60668-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TGIF2 (TGFB Induced Factor Homeobox 2) is a Protein Coding gene. Diseases associated with TGIF2 include Holoprosencephaly 4. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and mir34a and TGIF2 in osteoclastogenesis. The protein encoded by TGIF2 is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. TGIF2 is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between TGIF2 and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene.
Description
Rabbit Anti-TGIF2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Homeobox protein TGIF2; 5'-TG-3'-interacting factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2
Gene ID
60436
Accession Number
Q9GZN2
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human TGIF2 protein
Clonality
Polyclonal
Tag
TGIF2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
26kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of TGIF2 protein
Observed Molecular Weight
26
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Homeobox protein TGIF2; 5'-TG-3'-interacting factor 2; TGF-beta-induced transcription factor 2; TGFB-induced factor 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9GZN2
Isotype
Rabbit IgG

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