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T2R38 Polyclonal Antibody

CAT: 0749-ABP60588-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60588-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
T2R38 gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant) .
Description
Rabbit Anti-T2R38 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Taste receptor type 2 member 38; T2R38; PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61
Gene ID
5726
Accession Number
P59533
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human T2R38 protein at amino acid sequence of 180-260
Clonality
Polyclonal
Tag
T2R38
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
36kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of T2R38 protein
Observed Molecular Weight
36
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Taste receptor type 2 member 38; T2R38; PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P59533
Isotype
Rabbit IgG

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