Products for Research Use Only
RegisterLogin

SPHK1 Polyclonal Antibody

CAT: 0749-ABP60494-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP60494-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by SPHK1 catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for SPHK1.
Description
Rabbit Anti-SPHK1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Sphingosine kinase 1; SK 1; SPK 1; SPHK1; SPK
Gene ID
8877
Accession Number
Q9NYA1
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human SPHK1 protein at amino acid sequence of 160-240
Clonality
Polyclonal
Tag
SPHK1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of SPHK1 protein
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Sphingosine kinase 1; SK 1; SPK 1; SPHK1; SPK
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NYA1
Isotype
Rabbit IgG

Related Products

CatalogName
PPT-15425Human SPHK1 Recombinant Protein
KTE70383-01ELISA kit for Mouse Sphingosine kinase 1 (SPHK1)
KTE100218-01ELISA kit for Rat Sphingosine kinase 1 (SPHK1)
ABP55859-01SphK2 Polyclonal Antibody
ANT-14515-50ugSPHK2 Polyclonal Antibody
ANT-14515-100ugSPHK2 Polyclonal Antibody
ABP55858-01SphK2 (phospho Thr614) Polyclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody

Alternative Products

CatalogName
BT-AP14420-01SPHK1 Polyclonal Antibody
BS79564SPHK1 polyclonal antibody
TA358437SPHK1 Rabbit Polyclonal Antibody

Popular Products