SEC62 Polyclonal Antibody

• Background:

  SEC62 (SEC62 Homolog, Preprotein Translocation Factor) is a Protein Coding gene. Among its related pathways are Protein processing in endoplasmic reticulum and Unfolded Protein Response (UPR) . The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by SEC62 and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

• Description:

  Rabbit Anti-SEC62 Polyclonal Antibody

• Product Name Alternative:

  Translocation protein SEC62; Translocation protein 1; TP-1; hTP-1

• Gene ID:

  7095

• Accession Number:

  Q99442

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human SEC62 protein

• Clonality:

  Polyclonal

• Tag:

  SEC62

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  51kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of SEC62 protein

• Observed Molecular Weight:

  43

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Translocation protein SEC62; Translocation protein 1; TP-1; hTP-1

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q99442

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG