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RPA14 Polyclonal Antibody

CAT: 0749-ABP60234-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60234-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage (PubMed: 9430682) . In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. RPA3 (Replication Protein A3) is a Protein Coding gene. Diseases associated with RPA3 include Epidemic Typhus and Ovary Serous Adenocarcinoma. Among its related pathways are Mismatch repair and DNA Double-Strand Break Repair.
Description
Rabbit Anti-RPA14 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Replication protein A 14 kDa subunit; RP-A p14; Replication factor A protein 3; RF-A protein 3
Gene ID
6119
Accession Number
P35244
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RPA14 protein at amino acid sequence of 30-80
Clonality
Polyclonal
Tag
RPA14
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
14kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RPA14
Observed Molecular Weight
14
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
Replication protein A 14 kDa subunit; RP-A p14; Replication factor A protein 3; RF-A protein 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P35244
Isotype
Rabbit IgG

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