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RM02 Polyclonal Antibody

CAT: 0749-ABP60198-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60198-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MRPL2 (Mitochondrial Ribosomal Protein L2) is a Protein Coding gene. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL2 encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to MRPL2 is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Description
Rabbit Anti-RM02 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
39S ribosomal protein L2, mitochondrial; L2mt; MRP-L2; Mitochondrial large ribosomal subunit protein uL2m
Gene ID
51069
Accession Number
Q5T653
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human RM02 protein at amino acid sequence of 210-290
Clonality
Polyclonal
Tag
RM02
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
33kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RM02 protein
Observed Molecular Weight
33
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
39S ribosomal protein L2, mitochondrial; L2mt; MRP-L2; Mitochondrial large ribosomal subunit protein uL2m
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5T653
Isotype
Rabbit IgG

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