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RB6I2 Polyclonal Antibody

CAT: 0749-ABP60111-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60111-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1) is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t (10;12) (q11; p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. ERC1 is a Protein Coding gene. Diseases associated with ERC1 include Differentiated Thyroid Carcinoma and Distal Monosomy 12P. Among its related pathways are NF-kappa B signaling pathway and Cytoskeletal Signaling.
Description
Rabbit Anti-RB6I2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ELKS/Rab6-interacting/CAST family member 1; ERC-1; Rab6-interacting protein 2
Gene ID
23085
Accession Number
Q8IUD2
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human RB6I2 protein
Clonality
Polyclonal
Tag
RB6I2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
122kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RB6I2 protein
Observed Molecular Weight
122
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
ELKS/Rab6-interacting/CAST family member 1; ERC-1; Rab6-interacting protein 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8IUD2
Isotype
Rabbit IgG

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