Products for Research Use Only

PTN2 Polyclonal Antibody

CAT: 0749-ABP60031-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60031-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PTPN2 (Protein Tyrosine Phosphatase, Non-Receptor Type 2) is a Protein Coding gene. Diseases associated with PTPN2 include Rheumatoid Factor-Negative Juvenile Idiopathic Arthritis and Oligoarticular Juvenile Idiopathic Arthritis. Among its related pathways are Listeria monocytogenes entry into host cells and Jak-STAT signaling pathway (KEGG) . The protein encoded by PTPN2 is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of PTPN2, which suggested the roles in growth factor mediated cell signaling.
Description
Rabbit Anti-PTN2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Tyrosine-protein phosphatase non-receptor type 2; T-cell protein-tyrosine phosphatase; TCPTP
Gene ID
5771
Accession Number
P17706
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PTN2 protein
Clonality
Polyclonal
Tag
PTN2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
45kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PTN2 protein
Observed Molecular Weight
45
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Tyrosine-protein phosphatase non-receptor type 2; T-cell protein-tyrosine phosphatase; TCPTP
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P17706
Isotype
Rabbit IgG