PHC3 Polyclonal Antibody

• Background :

  PHC3 (Polyhomeotic Homolog 3) is a Protein Coding gene. Among its related pathways are Cellular Senescence (REACTOME) and SUMOylation. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A Lys-119, rendering chromatin heritably changed in its expressibility.

• Description :

  Rabbit Anti-PHC3 Polyclonal Antibody

• Product Name Alternative :

  Polyhomeotic-like protein 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3

• Gene ID :

  80012

• Accession Number :

  Q8NDX5

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human PHC3 protein at amino acid sequence of 720-800

• Clonality :

  Polyclonal

• Tag :

  PHC3

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  108kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of PHC3 protein

• Observed Molecular Weight :

  108

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Polyhomeotic-like protein 3; Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q8NDX5

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG