PDE7A Polyclonal Antibody

CAT: 0749-ABP59865-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59865-01Size:30 µL
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Background
The protein encoded by PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for PDE7A. PDE7A (Phosphodiesterase 7A) is a Protein Coding gene. Diseases associated with PDE7A include Chronic Lymphocytic Leukemia and Low Compliance Bladder. Among its related pathways are G alpha (s) signalling events and Ectoderm Differentiation.
Description
Rabbit Anti-PDE7A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; HCP1; TM22
Gene ID
5150
Accession Number
Q13946
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PDE7A protein
Clonality
Polyclonal
Tag
PDE7A
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
53kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PDE7A protein
Observed Molecular Weight
53
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; HCP1; TM22
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13946
Isotype
Rabbit IgG

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