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PACS1 Polyclonal Antibody

CAT: 0749-ABP59812-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59812-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PACS1 (Phosphofurin Acidic Cluster Sorting Protein 1) encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Description
Rabbit Anti-PACS1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Phosphofurin acidic cluster sorting protein 1; PACS-1
Gene ID
55690
Accession Number
Q6VY07
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PACS1 protein at amino acid sequence of 400-480
Clonality
Polyclonal
Tag
PACS1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
105kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PACS1 protein
Observed Molecular Weight
105
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Phosphofurin acidic cluster sorting protein 1; PACS-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6VY07
Isotype
Rabbit IgG

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BT-AP12729-01PACS1 Polyclonal Antibody
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