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PA21B Polyclonal Antibody

CAT: 0749-ABP59803-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59803-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PLA2G1B (Phospholipase A2 Group IB) encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs) . The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
Description
Rabbit Anti-PA21B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Phospholipase A2; Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B
Gene ID
5319
Accession Number
P04054
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PA21B protein at amino acid sequence of 70-150
Clonality
Polyclonal
Tag
PA21B
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
16kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PA21B protein
Observed Molecular Weight
16
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Phospholipase A2; Group IB phospholipase A2; Phosphatidylcholine 2-acylhydrolase 1B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P04054
Isotype
Rabbit IgG

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