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OPRX Polyclonal Antibody

CAT: 0749-ABP59648-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59648-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by OPRL1 is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand system modulates a variety of biological functions and neurobehavior, including stress responses and anxiety behavior, learning and memory, locomotor activity, and inflammatory and immune responses. A promoter region between OPRL1 and the 5'-adjacent RGS19 (regulator of G-protein signaling 19) gene on the opposite strand functions bi-directionally as a core-promoter for both genes, suggesting co-operative transcriptional regulation of these two functionally related genes. Alternatively spliced transcript variants have been described for OPRL1. A recent study provided evidence for translational readthrough in OPRL1 and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Description
Rabbit Anti-OPRX Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Nociceptin receptor; Kappa-type 3 opioid receptor; KOR-3; Orphanin FQ receptor
Gene ID
4987
Accession Number
P41146
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human OPRX protein
Clonality
Polyclonal
Tag
OPRX
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of OPRX protein
Observed Molecular Weight
40
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Nociceptin receptor; Kappa-type 3 opioid receptor; KOR-3; Orphanin FQ receptor
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P41146
Isotype
Rabbit IgG

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