OPA1 Polyclonal Antibody

CAT: 0749-ABP59646-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59646-01Size:30 µL
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Background
The protein encoded by OPA1 gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.
Description
Rabbit Anti-OPA1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1
Gene ID
4976
Accession Number
O60313
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human OPA1 protein
Clonality
Polyclonal
Tag
OPA1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
105kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of OPA1 protein
Observed Molecular Weight
105
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O60313
Isotype
Rabbit IgG

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