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OLR1 Polyclonal Antibody

CAT: 0749-ABP59644-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59644-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OLR1 encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. OLR1 is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of OLR1 have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-OLR1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
C-type lectin domain family 8 member A; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-type oxidized LDL receptor 1
Gene ID
4973
Accession Number
P78380
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human OLR1 protein at amino acid sequence of 60-140
Clonality
Polyclonal
Tag
OLR1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
30kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of OLR1 protein
Observed Molecular Weight
30
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
C-type lectin domain family 8 member A; Lectin-like oxidized LDL receptor 1; LOX-1; Lectin-type oxidized LDL receptor 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P78380
Isotype
Rabbit IgG

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