OCLN Polyclonal Antibody

• Background :

  OCLN gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1. Mb downstream on the q arm of chromosome 5.

• Description :

  Rabbit Anti-OCLN Polyclonal Antibody

• Product Name Alternative :

  Occludin

• Gene ID :

  100506658

• Accession Number :

  Q16625

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from part region of human OCLN protein

• Clonality :

  Polyclonal

• Tag :

  OCLN

• Applications :

  WB IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  57kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of OCLN protein

• Observed Molecular Weight :

  57

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IF 1:100-300; ELISA 1:5000-20000; Not yet tested in other applications.

• Other Product Names :

  Occludin

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q16625

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG