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NTHL1 Polyclonal Antibody

CAT: 0749-ABP59546-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59546-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NTHL1 encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. NTHL1 (Nth Like DNA Glycosylase 1) is a Protein Coding gene. Diseases associated with NTHL1 include Familial Adenomatous Polyposis 3 and Periampullary Adenoma. Among its related pathways are DNA damage_Role of Brca1 and Brca2 in DNA repair and Telomere C-strand (Lagging Strand) Synthesis.
Description
Rabbit Anti-NTHL1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Endonuclease III-like protein 1; hNTH1; Bifunctional DNA N-glycosylase/DNA- (apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase
Gene ID
4913
Accession Number
P78549
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human NTHL1 protein
Clonality
Polyclonal
Tag
NTHL1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
34kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NTHL1 protein
Observed Molecular Weight
34
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Endonuclease III-like protein 1; hNTH1; Bifunctional DNA N-glycosylase/DNA- (apurinic or apyrimidinic site) lyase; DNA glycosylase/AP lyase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P78549
Isotype
Rabbit IgG

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