NR2E3 Polyclonal Antibody

• Background :

  Nuclear Receptor Subfamily 2 Group E Member 3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. NR2E3 encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in NR2E3 are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

• Description :

  Rabbit Anti-NR2E3 Polyclonal Antibody

• Product Name Alternative :

  Photoreceptor-specific nuclear receptor; Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor

• Gene ID :

  10002

• Accession Number :

  Q9Y5X4

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human NR2E3 protein

• Clonality :

  Polyclonal

• Tag :

  NR2E3

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  45kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of NR2E3 protein

• Observed Molecular Weight :

  45

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Photoreceptor-specific nuclear receptor; Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9Y5X4

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG