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NPHP1 Polyclonal Antibody

CAT: 0749-ABP59506-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59506-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NPHP1 (Nephrocystin 1) is a Protein Coding gene. Diseases associated with NPHP1 include Senior-Loken Syndrome-1 and Nephronophthisis 1, Juvenile. Among its related pathways are Organelle biogenesis and maintenance and Regulation of PLK1 Activity at G2/M Transition. NPHP1 encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures.
Description
Rabbit Anti-NPHP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Nephrocystin-1; Juvenile nephronophthisis 1 protein
Gene ID
4867
Accession Number
O15259
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human NPHP1 protein at amino acid sequence of 510-590
Clonality
Polyclonal
Tag
NPHP1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
80kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of NPHP1 protein
Observed Molecular Weight
80
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Nephrocystin-1; Juvenile nephronophthisis 1 protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O15259
Isotype
Rabbit IgG

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