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MXI1 Polyclonal Antibody

CAT: 0749-ABP59349-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59349-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. MAX Interactor 1, Dimerization Protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Description
Rabbit Anti-MXI1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Max-interacting protein 1; Max interactor 1; Class C basic helix-loop-helix protein 11; bHLHc11
Gene ID
4601
Accession Number
P50539
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human MXI1 protein
Clonality
Polyclonal
Tag
MXI1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MXI1 protein
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Max-interacting protein 1; Max interactor 1; Class C basic helix-loop-helix protein 11; bHLHc11
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P50539
Isotype
Rabbit IgG

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