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MFGM Polyclonal Antibody

CAT: 0749-ABP59266-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59266-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MFGE8 encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA) . Alternative splicing results in multiple transcript variants. MFGE8 (Milk Fat Globule-EGF Factor 8 Protein) is a Protein Coding gene. Diseases associated with MFGE8 include Opisthorchiasis and Anal Paget's Disease. Among its related pathways are Integrins in angiogenesis and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3.
Description
Rabbit Anti-MFGM Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Lactadherin; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1
Gene ID
4240
Accession Number
Q08431
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human MFGM protein
Clonality
Polyclonal
Tag
MFGM
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MFGM protein
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Lactadherin; Breast epithelial antigen BA46; HMFG; MFGM; Milk fat globule-EGF factor 8; MFG-E8; SED1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q08431
Isotype
Rabbit IgG

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