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MDFIC Polyclonal Antibody

CAT: 0749-ABP59244-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59244-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MDFIC (MyoD Family Inhibitor Domain Containing) is a Protein Coding gene. Diseases associated with MDFIC include T-Cell Leukemia and Hiv-1. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription. MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.
Description
Rabbit Anti-MDFIC Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MyoD family inhibitor domain-containing protein; I-mfa domain-containing protein; hIC
Gene ID
29969
Accession Number
Q9P1T7
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human MDFIC protein at amino acid sequence of 100-180
Clonality
Polyclonal
Tag
MDFIC
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
27kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MDFIC protein
Observed Molecular Weight
27
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
MyoD family inhibitor domain-containing protein; I-mfa domain-containing protein; hIC
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9P1T7
Isotype
Rabbit IgG

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