MDFIC Polyclonal Antibody

• Background :

  MDFIC (MyoD Family Inhibitor Domain Containing) is a Protein Coding gene. Diseases associated with MDFIC include T-Cell Leukemia and Hiv-1. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription. MDFIC product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

• Description :

  Rabbit Anti-MDFIC Polyclonal Antibody

• Product Name Alternative :

  MyoD family inhibitor domain-containing protein; I-mfa domain-containing protein; hIC

• Gene ID :

  29969

• Accession Number :

  Q9P1T7

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human MDFIC protein at amino acid sequence of 100-180

• Clonality :

  Polyclonal

• Tag :

  MDFIC

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  27kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of MDFIC protein

• Observed Molecular Weight :

  27

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  MyoD family inhibitor domain-containing protein; I-mfa domain-containing protein; hIC

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9P1T7

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG