Products for Research Use Only

M3K14 Polyclonal Antibody

CAT: 0749-ABP59175-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59175-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. MAP3K14 is a Protein Coding gene. Diseases associated with MAP3K14 include Nik Deficiency. Among its related pathways are 4-1BB Pathway and RANK Signaling in Osteoclasts.
Description
Rabbit Anti-M3K14 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK
Gene ID
9020
Accession Number
Q99558
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human M3K14 protein at amino acid sequence of 90-170
Clonality
Polyclonal
Tag
M3K14
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
104kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of M3K14 protein
Observed Molecular Weight
104
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Mitogen-activated protein kinase kinase kinase 14; NF-kappa-beta-inducing kinase; HsNIK; Serine/threonine-protein kinase NIK
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99558
Isotype
Rabbit IgG