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LRP1B Polyclonal Antibody

CAT: 0749-ABP59145-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59145-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor family have roles related to clearance of extracellular ligand and are proposed to be involved in extracellular signal transduction. silencing and down-expression of LRP1B as been observed in renal cell carcinoma and thyroid cancer. Further Deletion of LRP1B has been associated with chemotherapy resistance in high-grade serous cancers.
Description
Rabbit Anti-LRP1B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Low-density lipoprotein receptor-related protein 1B; LRP-1B; Low-density lipoprotein receptor-related protein-deleted in tumor; LRP-DIT
Gene ID
53353
Accession Number
Q9NZR2
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human LRP1B protein at amino acid sequence of 200-280
Clonality
Polyclonal
Tag
LRP1B
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
505kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of LRP1B protein
Observed Molecular Weight
505
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Low-density lipoprotein receptor-related protein 1B; LRP-1B; Low-density lipoprotein receptor-related protein-deleted in tumor; LRP-DIT
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9NZR2
Isotype
Rabbit IgG

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