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LRP11 Polyclonal Antibody

CAT: 0749-ABP56787-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP56787-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LRP1 (low density lipoprotein related protein), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF) -like repeats, YWTD repeats and an O-linked sugar domain. LRP11 (low density lipoprotein receptor-related protein 11), also known as MANSC3, is a 500 amino acid single-pass type I membrane protein that exists as two alternatively spliced isoforms. LRP11 is encoded by a gene located on human chromosome 6q25. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Description
Rabbit Anti-LRP11 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
LRP11; Low-density lipoprotein receptor-related protein 11; LRP-11
Gene ID
84918
Accession Number
Q86VZ4
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human LRP11 at AA range: 20-100
Clonality
Polyclonal
Tag
Low-density lipoprotein receptor-related protein 11
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
50kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
LRP11 Polyclonal Antibody detects endogenous levels of LRP11 protein.
Observed Molecular Weight
50
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
LRP11; Low-density lipoprotein receptor-related protein 11; LRP-11
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q86VZ4
Isotype
Rabbit IgG

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