LITAF Polyclonal Antibody

CAT: 0749-ABP59126-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP59126-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. LITAF encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of LITAF is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in LITAF cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for LITAF.
Description
Rabbit Anti-LITAF Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Small integral membrane protein of lysosome/late endosome; p53-induced gene 7 protein
Gene ID
9516
Accession Number
Q99732
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human LITAF protein
Clonality
Polyclonal
Tag
LITAF
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
17kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of LITAF protein
Observed Molecular Weight
17
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Small integral membrane protein of lysosome/late endosome; p53-induced gene 7 protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q99732
Isotype
Rabbit IgG

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