Products for Research Use Only
RegisterLogin

KGP1 Polyclonal Antibody

CAT: 0749-ABP59036-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP59036-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Mammals have three different isoforms of cyclic GMP-dependent protein kinase (Ialpha, Ibeta, and II) . These PRKG isoforms act as key mediators of the nitric oxide/cGMP signaling pathway and are important components of many signal transduction processes in diverse cell types. This PRKG1 gene on human chromosome 10 encodes the soluble Ialpha and Ibeta isoforms of PRKG by alternative transcript splicing. A separate gene on human chromosome 4, PRKG2, encodes the membrane-bound PRKG isoform II. The PRKG1 proteins play a central role in regulating cardiovascular and neuronal functions in addition to relaxing smooth muscle tone, preventing platelet aggregation, and modulating cell growth. This gene is most strongly expressed in all types of smooth muscle, platelets, cerebellar Purkinje cells, hippocampal neurons, and the lateral amygdala. Isoforms Ialpha and Ibeta have identical cGMP-binding and catalytic domains but differ in their leucine/isoleucine zipper and autoinhibitory sequences and therefore differ in their dimerization substrates and kinase enzyme activity.
Description
Rabbit Anti-KGP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CGMP-dependent protein kinase 1; cGK 1; cGK1; cGMP-dependent protein kinase I; cGKI
Gene ID
5592
Accession Number
Q13976
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human KGP1 protein
Clonality
Polyclonal
Tag
KGP1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
73kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of KGP1 protein
Observed Molecular Weight
73
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
CGMP-dependent protein kinase 1; cGK 1; cGK1; cGMP-dependent protein kinase I; cGKI
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13976
Isotype
Rabbit IgG

Related Products

CatalogName
ANT-13852-100ugPorphyromonas gingivalis kgp / prtK Polyclonal Antibody
ANT-13852-50ugPorphyromonas gingivalis kgp / prtK Polyclonal Antibody
ANT-13843-100ugPolyclonal Antibody
ANT-15047-100ugWAS Polyclonal Antibody
ANT-15047-50ugWAS Polyclonal Antibody
ANT-13843-50ugPolyclonal Antibody
ABP51603-01IKKBeta Polyclonal AntibodyIKKβ Polyclonal Antibody
ABP50715-01AR-Beta2 Polyclonal AntibodyAR-β2 Polyclonal Antibody
ABP51469-01GPR83 Polyclonal Antibody
ABP60870-01VANG2 Polyclonal Antibody

Alternative Products

CatalogName
BT-AP10675-01KGP1 Polyclonal Antibody
MBS9515132-01KGP1 Rabbit Polyclonal Antibody
WP2289-01U-Blot® KGP1 Polyclonal Antibody
PAV1992Rabbit Anti-KGP1/PRKG1 Polyclonal Antibody
C44385-01KGP1 Antibody
STJ191983Anti-KGP1 antibody
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody
APR00451GPolyclonal SPI1 polyclonal antibody

Popular Products