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ITBP1 Polyclonal Antibody

CAT: 749-ABP58979-01Size: 30 µLDry Ice: NoHazardous: No
30 µLSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The cytoplasmic domains of integrins are essential for cell adhesion. The Integrin Subunit Beta 1 Binding Protein 1 encoded by ITGB1BP1 binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.
Description
Rabbit Anti-ITBP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; ICAP-1
Gene ID
9270
Accession Number
O14713
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human ITBP1 protein
Clonality
Polyclonal
Tag
ITBP1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of ITBP1 protein
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Integrin beta-1-binding protein 1; Integrin cytoplasmic domain-associated protein 1; ICAP-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14713
Isotype
Rabbit IgG

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