INVS Polyclonal Antibody

CAT: 0749-ABP58956-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58956-01Size:30 µL
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Background
INVS (Inversin) is a Protein Coding gene. Diseases associated with INVS include Nephronophthisis 2, Infantile and Nephronophthisis 16. Among its related pathways are Wnt Signaling Pathway and Pluripotency. INVS encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in INVS have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for INVS.
Description
Rabbit Anti-INVS Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Inversin; Inversion of embryo turning homolog; Nephrocystin-2
Gene ID
27130
Accession Number
Q9Y283
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human INVS protein
Clonality
Polyclonal
Tag
INVS
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
117kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of INVS protein
Observed Molecular Weight
117
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Inversin; Inversion of embryo turning homolog; Nephrocystin-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9Y283
Isotype
Rabbit IgG

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