INT6 Polyclonal Antibody

• Background:

  DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH) . Multiple transcript variants encoding different isoforms have been found for this gene. INT6 (Integrator Complex Subunit 6) is a Protein Coding gene. Among its related pathways are RNA polymerase II transcribes snRNA genes and Gene Expression.

• Description:

  Rabbit Anti-INT6 Polyclonal Antibody

• Product Name Alternative:

  Integrator complex subunit 6; Int6; DBI-1; Protein DDX26; Protein deleted in cancer 1; DICE1

• Gene ID:

  26512

• Accession Number:

  Q9UL03

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human INT6 protein at amino acid sequence of 550-630

• Clonality:

  Polyclonal

• Tag:

  INT6

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  97kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of INT6 protein

• Observed Molecular Weight:

  97

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Integrator complex subunit 6; Int6; DBI-1; Protein DDX26; Protein deleted in cancer 1; DICE1

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q9UL03

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG