HPS5 Polyclonal Antibody

• Background :

  HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in HPS5 are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for HPS5. HPS5 (HPS5, Biogenesis Of Lysosomal Organelles Complex 2 Subunit 2) is a Protein Coding gene. Diseases associated with HPS5 include Hermansky-Pudlak Syndrome 5 and Hermansky-Pudlak Syndrome Without Pulmonary Fibrosis. An important paralog of HPS5 is TECPR2.

• Description :

  Rabbit Anti-HPS5 Polyclonal Antibody

• Product Name Alternative :

  Hermansky-Pudlak syndrome 5 protein; Alpha-integrin-binding protein 63; Ruby-eye protein 2 homolog; Ru2

• Gene ID :

  11234

• Accession Number :

  Q9UPZ3

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from part region of human HPS5 protein

• Clonality :

  Polyclonal

• Tag :

  HPS5

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  124kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  The antibody detects endogenous levels of HPS5 protein

• Observed Molecular Weight :

  124

• Formulation :

  Liquid solution

• Buffer pH :

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names :

  Hermansky-Pudlak syndrome 5 protein; Alpha-integrin-binding protein 63; Ruby-eye protein 2 homolog; Ru2

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q9UPZ3

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG