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HPS5 Polyclonal Antibody

CAT: 0749-ABP58814-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58814-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HPS5 encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 6 protein and may interact with the cytoplasmic domain of integrin, alpha-3. Mutations in HPS5 are associated with Hermansky-Pudlak syndrome type 5. Multiple transcript variants encoding two distinct isoforms have been identified for HPS5. HPS5 (HPS5, Biogenesis Of Lysosomal Organelles Complex 2 Subunit 2) is a Protein Coding gene. Diseases associated with HPS5 include Hermansky-Pudlak Syndrome 5 and Hermansky-Pudlak Syndrome Without Pulmonary Fibrosis. An important paralog of HPS5 is TECPR2.
Description
Rabbit Anti-HPS5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Hermansky-Pudlak syndrome 5 protein; Alpha-integrin-binding protein 63; Ruby-eye protein 2 homolog; Ru2
Gene ID
11234
Accession Number
Q9UPZ3
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human HPS5 protein
Clonality
Polyclonal
Tag
HPS5
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
124kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of HPS5 protein
Observed Molecular Weight
124
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Hermansky-Pudlak syndrome 5 protein; Alpha-integrin-binding protein 63; Ruby-eye protein 2 homolog; Ru2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9UPZ3
Isotype
Rabbit IgG

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