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FAT1 Polyclonal Antibody

CAT: 0749-ABP58531-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58531-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 product has five epidermal growth factor (EGF) -like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.
Description
Rabbit Anti-FAT1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Protocadherin Fat 1; Cadherin family member 7; Cadherin-related tumor suppressor homolog; Protein fat homolog; Protocadherin Fat 1, nuclear form
Gene ID
2195
Accession Number
Q14517
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human FAT1 protein at amino acid sequence of 1140-1220
Clonality
Polyclonal
Tag
FAT1
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
504kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of FAT1 protein
Observed Molecular Weight
504
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Protocadherin Fat 1; Cadherin family member 7; Cadherin-related tumor suppressor homolog; Protein fat homolog; Protocadherin Fat 1, nuclear form
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14517
Isotype
Rabbit IgG

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